Posts made in April, 2020

What Are the Best Qualities Every Tenant Should Have?

»Posted by on Apr 27, 2020 in Renting Services | 0 comments

A great landlord would go for the extra mile just to get a qualified occupant for ones’ rental property. Tenants are considered as qualified once they have rule-abiding behavior and a guaranteed financial responsibilities’ track record. These qualities only signify that they can rent your property and won’t damage it. However, a good landlord would wish to have a tenant who does not only possess a good credit score but also tenants who have a clean criminal background. Though it’s really challenging to screen for prospective tenants, particular qualities make you, as a renter, to be the outstanding tenant in the eyes of your landlord. Here are some of them according to the best property management companies Inglewood:

Never allow someone to live with you who isn’t included on the lease

Lease contracts are intended to secure both the tenants and the landlord. It should be signed by anyone who lives in that rental property that’s over 18 years old. A great renter won’t secretly sneak in someone they know. The best thing to do in this case would be to let your landlord know when you’re planning to host a long-term visitor.

Be low-maintenance

Though a landlord would appreciate good communication from their occupants, a tenant who always need special attention or complains all the time is stressful. In several instances, you are probably not the only tenant your landlord handles and you’re not the only priority in the business. As much as possible, attempt to solve any issues you can see on your own but make sure to still refer and adhere to the lease terms. العاب تربح منها المال If it’s way beyond your capability, that would be the best time to contact your landlord.

Communicate issues about repair or maintenance

Even the tiniest leak could lead to a major expensive issue for property owners. An ideal tenant will let the landlord know right away as soon as they observe any maintenance problem that needs to be attended. Landlords could offer easy options for tenants to pass requests for property maintenance online to easily be monitored and tracked until the problem is fixed.

Treat the place as if it’s your own

By managing your rental property and taking pride in it as if it’s your own won’t only guarantee that you can retrieve your security deposit, it could also develop an excellent landlord recommendation if ever you plan to move in eventually. It is expected for current amenities to get wear and tear, however, avoiding property damage caused by tenants is really a commendable trait.

Pay your rent

Every landlord loves to have tenants who pay rent right on the dot. The relationship between tenant and landlord rotates around routine rent payments in return for a place to live. الكرابس Paying on time is one of the most crucial tasks, which the tenants are responsible for. Typically, your landlord is dependent on the rent you pay every month to pay for their property’s mortgage. Hence, once you fail to pay on time, your landlord could have a financial problem. لعب القمار على الانترنت

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Heroin and opiates the national health and wellbeing charity

»Posted by on Apr 8, 2020 in Sober living | 0 comments

There are many drugs in this group and some, such as diazepam , are prescribed as medicines in the UK. Our professional, counsellors and therapists will do all they can to help you make a full recovery. You can find out more by calling our 24/7 helpline and speaking in confidence to one of our addiction treatment experts. We understand that fear and shame can hold back someone who needs help from seeking it. It is important to understand that addiction never gets better on its own and that untreated drug addiction can often be fatal. Mixing any benzodiazepine with another CNS depressant drug is extremely dangerous, even more so when the drugs are counterfeit and their strength and content are unknown to the user.

  • You should seek help the moment you realise that your use of a benzodiazepines is slipping out of your control.
  • If you’re hooked on any of these drugs, it’s important to find out more about your addiction so that you know what you’re dealing with and the right steps to take.
  • Epidemiologic studies suggest that 22% of U.S. adults experience chronic pain and 7% moderate to severe pain .
  • Among males, there were 109.7 drug poisoning deaths registered per million in 2020 , compared with 49.8 deaths per million among females .
  • Handling of health-related data of a deceased individual does not need consent, as one relies on other legal bases than consent for processing these data.
  • Additional data on Scottish drug-related deaths are available from theInformation Services Division of NHS Scotland.

Avoid taking other drugs or more benzodiazepines to deal with withdrawal symptoms. It is extremely dangerous to mix benzodiazepines with other depressant/downer drugs like alcohol, gabapentin and opioids . Users of the Ksalol and Xanax are known to be mostly teenagers and heroin addicts.

Uncooperative, aggressive or stressed cats are commonly encountered in the veterinary clinic. This article examines the aims for calming these patients, the importance of planning and considers selected sedative protocols. Sadly, complications can occur during the peri-anaesthetic period with potentially detrimental effects on the patient. In this article Lou Northway, VNCertECC NCert RVN, examines the most common causes of adverse peri-anaesthetic events and the steps that can be taken to reduce their incidence. In this fourth instalment of our C-section series we explore induction of anaesthesia for the Ceasarean patient and the techniques and drugs that may be used. Almost all patients presenting for a surgical procedure to be performed under general anaesthesia will receive a form of pre-anaesthetic medication.

What is Benzodiazepines Addiction?

Use of non-prescription opioids to medicate a health problem is strongly negatively correlated with ultimate heroin use . Boscarino et al. , in a large interview survey of a clinic population, reported a lifetime prevalence of mild OUD [2–3 DSM-5 symptoms ] of 28.1%, moderate OUD (4–5 symptoms) of 9.7%, and severe OUD (6+ symptoms) of 3.5%. It is worth noting that item 1 of the DSM-5 criteria would likely be endorsed by a large percentage of patients treated for chronic pain.

  • They typically use the drug in incremental doses to continue to up their ‘highs’ and feelings of pleasure.
  • The sample consisted of 78,976 respondents aged 12 years or older living in households or non-institutional group housing who were representative of non-elderly US adults in 2015–2016.
  • The plasma elimination half-life of diazepam is 3.2 hours in the dog3, with an even longer half-life for the active metabolite desmethyldiazepam3,4.
  • Benzodiazepine addiction is a debilitating illness, one which should be treated under the supervision of trained medical professionals.

We have extended our anaesthesia and analgesia portfolio with the launch of AceSedate®. Containing the tried and trusted, long-acting sedative agent acepromazine as its active ingredient, AceSedate can be used for the premedication, sedation and tranquilisation of cats and dogs. In this article we examine why methadone could be considered the analgesic of choice for many of our patients and understand its importance in modern veterinary medicine. This scientific paper assessed whether the American Society of Anesthesiologists Physical Status Classification correlated with the risk of anaesthetic death in dogs and cats. In this summary of a study by Miller et al we examine if there are any benefits to an alfaxalone/midazolam induction over alfaxalone alone in the healthy dog. Pulse oximetry is one of the most commonly performed monitoring procedures in veterinary anaesthesia.

In a large survey of a clinic population, among participants who acknowledged only 2–3 symptoms , 33.7% endorsed item 1, 88.1% item 2, 44.7% item 4, and 23.8% item 7 . These data suggest a need to refine our operational measures of OUD [see Fishbain et al. for extended consideration of this issue]. Because the people caught up in the crisis live substantially off the medical grid until they die, it is difficult to know exactly who they are. However, a recent study has provided a great deal of information about this population. Of the sample, 23,452 (29.7%) interviewees had used prescription opioids, 3,913 (4.95%) reported prescription opioid misuse, 648 (0.82%) prescription abuse (defined by DSM-4 criteria), and 451 (0.57%) heroin use. These individuals were more likely to report fair or poor health (15.5, 24.9, and 17.6%); a chronic health condition; any disability (22.5, 35.7, and 26.0%); and impairment of mental health .


These drugs can be easily abused due to the rush of euphoria they cause when taken. You may want to sleep faster or feel more pleasure than what simple doses can accomplish and up your dose as a result. Recreational users tend to abuse benzos quickly because they want to feel an increased sense of euphoria. At low doses, you’ll experience relaxation, sedation, drowsiness, anxiety/stress relief, and increased self-esteem. Taking lower doses of benzodiazepines produces similar sensations to one or two bottles of alcohol.

Since the COVID-19 lockdown, there has been a shortage of heroin available worldwide. The content of each pill can vary tremendously, and this has been the cause of many overdoses. One of the biggest contributing risk factors for benzo addiction is how easily accessible this drug is.

The first being the lack of a comparable healthy control group comprising of deceased individuals who were not polysedative users. The lack of a comparable group of living polysedative users may also be considered a limitation as such group would have provided context to the limited and opportunistic sample comprising DDs. Methodological limitations include the inability to extract dosage and duration of substance use due to the nature of the information being obtained from routine PMRs.

  • This means that around half of the deaths reported in this bulletin will have occurred in the previous year.
  • In 2020, the highest rate of drug misuse deaths was observed in the North East (104.6 deaths per million; 258 registered deaths), while the lowest rate was in London (33.1 deaths per million; 296 deaths).
  • Some studies failed to find any association between chronic opioid use with the increased risk of CVD (Chen and Ashburn, 2015; Chou et al., 2015).
  • The risk of suicide and drug-related deaths among prisoners, based on confidential matching of data from HM Prison and Probation Service and Office for National Statistics mortality records.

The less active metabolites of midazolam make it more suitable for infusions6. Accumulation of BDZ metabolites can also occur in animals experiencing renal failure4, and juveniles, geriatrics and liver disease patients may experience increases in elimination half-life with resultant prolonged activity1. The first UK-wide mental health and money advice service dedicated to supporting people affected by mental health and money issues. This organisation gives support and advice to people who are taking prescribed benzodiazepines, antidepressants and sleeping tablets.

The current study did also reveal a significant, albeit small, association between the presence of opioids in post-mortem cases and inflammation severity. Recently, research suggested that chronic inflammation is one the leading causes of cardiac diseases (Fioranelli et al., 2018). Alcohol is the most common CNS depressant used to boost the effects of benzodiazepines. Mixing benzodiazepines with alcohol can easily lead to a dangerous case of overdose and withdrawing from both substances at once can also be lethal. While these drugs are known to be effective for treating these conditions, they possess a high potential for abuse. When taken, they increase the effects of a chemical known as gamma-aminobutyric acid in receptors in the brain, which leads to sedative, hypnotic, and euphoric feelings.

The risks

It can be administered for analgesia of moderate to severe pain in dogs and cats, to provide neuroleptanalgesia, and as part of a patient’s premedication protocol prior to general anaesthesia. Mortality rates for deaths related to drug poisoning and drug misuse, and average registration delay, by local authority, England and Wales. Annual number of deaths registered related to drug poisoning in England and Wales by sex, region and whether selected substances were mentioned anywhere on the death certificate, without other drugs and with or without alcohol. Males accounted for more than two-thirds of registered drug poisonings in 2020 , consistent with previous years. The male age-standardised rate increased from 104.7 deaths per million in 2019 to 109.7 in 2020, while the female age-standardised rate increased from 49.1 per million in 2019 to 49.8 in 2020.

Relief of pain was reported as the most common reason for opioid misuse (66.3%) and opioid abuse (48.7%). Among respondents who reported misuse or abuse, opioids were most often obtained from a physician (35.1 and 44.3%, respectively) or a friend or relative (53.1 and 35.9%) eco sober house complaints and were uncommonly obtained from a stranger or drug dealer (3.1 and 13.8%). The study by Han et al. suggests that opioid abuse is relatively rare among patients prescribed opioids (2.1%) and in 48.7% of cases, search for pain relief is the major driving factor.

Depending on the potency of each individual benzodiazepines, they’ll be classed into different categories. Commonly known benzos like Alprazolam and Diazepam are Schedule IV drugs in the US and Canada, and Class C drugs in the UK. Using benzodiazepines over a long period is not advised due to the risks of becoming addicted and suffering the adverse effects that come with addiction to this class of drugs. However, the risks of benzodiazepines began to draw concern, particularly when the drugs’ potential for dependence became obvious in the 1980s. This subsequently led to the largest-ever class-action lawsuit filed against pharmaceutical companies in the history of Great Britain.

Many efforts to address the opioid crisis, including those by the CDC , appear to have conflated the operative mechanisms in these two epochs , even as the CDC now explicitly recognizes them . Further evidence suggests that opioids can elevate the level and accelerate the formation of reactive oxygen species which results in vascular cell damage and endothelial dysfunction (Zahmatkesh et al., 2017). Sociodemographic characteristics at the time of death and drug classes identified in the 436 PMRs are depicted in Tables 1, 2. CVD pathologies and their respective severity scores are listed in Table 3.

benzos vs.opiates

Treatment for benzodiazepines addiction doesn’t make you immune to using again and subsequently becoming addicted. Treatment and rehab will equip you with strategies that will help you stay sober in the long run. You have to employ these methods and techniques and also get support after your treatment is over. If your addiction started from a medical condition like insomnia or anxiety, through rehab, you’ll be taught alternative ways to manage these conditions.

Paper summary: Intramuscular butorphanol/alfaxalone combination for sedation of cats prior to echocardiography

Both midazolam and diazepam undergo initial oxidation followed by conjugation via the cytochrome P450 system in the liver1. If you’re affected by your medication, you shouldn’t drive until the effects wear off. If you have a panic disorder, you may benefit from cognitive behavioural therapy whilst you are coming off the medication. Talk to your doctor about stopping if you have been taking benzodiazepines regularly for 4 weeks or more. Figures from other sources may not be comparable to those presented here for England and Wales, because of differences in data collection methods and in the death registration system.

Hs-CRP is known to be an important molecular biomarker in activating innate and adaptive immune response to inflammation . Hs-CRP is mainly produced under the influence of IL-6, and the literature evidence suggests that hs-CRP is correlated with the pathophysiology of atherosclerosis and coronary artery disease . Specifically, of the 1,264 DDs reported in 2019, 1,205 were related to opioid use (e.g., heroin, morphine, methadone), and 1,040 to additional street and/or prescribed benzodiazepine use (e.g., diazepam, etizolam). According to the Royal College of Psychiatrists, addiction to benzodiazepines occurs in 40% of people who take the drug for longer than six weeks.

With the current pandemic of COVID-19, opioids use has also contributed to increasing the risk of COVID-19 infection and the risk of its adverse effects (Wang et al., 2021). Specifically, patients diagnosed with substance use disorders were at about 8 times higher risk of contracting and perishing from COVID-19 compared non-users. This risk was even greater for patients affected by opioid use disorder (Wang et al., 2021).

All of this means that people who use benzodiazepines will often be taking a much more potent and more dangerous drug than they think they are, or the tablet’s markings might suggest. They often come in blister packs, which can make them look legitimate and safe but they are not. The tablets are usually sold as diazepam or alprazolam but don’t often contain any of the drug they are sold as. Instead they might contain other dangerous benzodiazepines, their analogues or other chemicals.

The reasons for the high variability in opioid dosage needed to achieve control of chronic pain are not well-understood. Genetic differences in hepatic metabolism can account for 3-fold or greater variability . Genetic differences in the receptor interactions of different opioids and in neural transmission also appear to be important .

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